Serotonin stimulates lateral habenula via activation of the post-synaptic serotonin 2/3 receptors and transient receptor potential channels
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文摘
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5-HT induced an inward current (I(5-HTi)) and increased firing in ∼80% LHb cells.

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A 5-HT uptake blocker induced I(5-HTi), indicating endogenous 5-HT activity.

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I(5-HTi) was blocked/activated by 5-HT2/3 antagonists/agonists.

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A transient receptor potential channel blocker inhibited I(5-HTi).

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