Evaluation of a von Willebrand factor three test panel and chemiluminescent-based assay system for identification of, and therapy monitoring in, von Willebrand disease
文摘

von Willebrand disease (VWD) is the most common bleeding disorder and arises from deficiency and/or defects of von Willebrand factor (VWF).

Laboratory diagnosis and typing of VWD requires a wide range of tests, including VWF antigen and various activities.

We assessed the ACL AcuStar™, and an associated HemosIL AcuStar three test panel, for ability to identify and provisionally type VWD.

This test system was compared to previously evaluated and validated test systems and the study employed a large total sample test set (n= 535).

This study is the first independent evaluation of the HemosIL VWF:CB, and the comprehensive three chemiluminescent-based VWF test panel set.

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