Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

详细信息查看全文

作者：Sarah K. Denny¹ ; ¹⁰ ; Dian Yang² ; ¹⁰ ; Chen-Hua Chuang³ ; Jennifer J. Brady³ ; Jing Shan Lim² ; Barbara M. Grü ; ner³ ; Shin-Heng Chiou³ ; Alicia N. Schep³ ; Jessika Baral³ ; Cé ; cile Hamard⁷ ; Martine Antoine⁷ ; Marie Wislez⁷ ; Christina S. Kong⁴ ; Andrew J. Connolly⁴ ; Kwon-Sik Park⁸ ; Julien Sage² ; ³ ; ⁵ ; ⁶ ; ¹¹ ; William J. Greenleaf¹ ; ³ ; ⁹ ; ¹¹ ; ^{wjg@stanford.edu" class="auth_mail" title="E-mail the corresponding author} ; Monte M. Winslow² ; ³ ; ⁴ ; ⁵ ; ¹¹ ; ^{mwinslow@stanford.edu" class="auth_mail" title="E-mail the corresponding author}
刊名：Cell
出版年：2016
出版时间：14 July 2016
年：2016
卷：166
期：2
页码：328-342
全文大小：5277 K

文摘

•: SCLC metastases have profound chromatin changes compared to primary tumors
•: Nfib drives an increase of chromatin accessibility at distal regulatory elements
•: Nfib is necessary and sufficient for metastatic ability in vivo
•: Nfib co-opts pro-metastatic neuronal gene expression programs

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.