Participation of peripheral TRPV1, TRPV4, TRPA1 and ASIC in a magnesium sulfate-induced local pain model in rat

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Participation of peripheral TRPV1, TRPV4, TRPA1 and ASIC in a magnesium sulfate-induced local pain model in rat

详细信息查看全文

作者：Dragana Srebro ; ^{srebrodragana1@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Sonja Vučković ; Milica Prostran
关键词：[d ; (g)] ; difference in pressures ; AA% ; analgesic activity ; AITC ; allyl isothiocyanate ; ANOVA ; analysis of variance ; ASIC ; acid-ion sensing channel ; MS ; magnesium sulfate ; NMDA ; N-methyl-d-aspartate receptors ; NO ; nitric oxide ; PWT ; paw withdrawal threshold ; TRP ; transient receptor potential ; TRPA1 ; ankyrin 1 ; TRPM ; TRP melastatin types 6 and 7 ; TRPV1 ; vanilloid 1 ; TRPV4 ; vanilloid 4
刊名：Neuroscience
出版年：2016
出版时间：17 December 2016
年：2016
卷：339
期：Complete
页码：1-11
全文大小：1192 K

文摘

•: Subcutaneous injection of isotonic solution of magnesium sulfate (MS) produces local pain.
•: MS modulates the activity of TRPV1, TRPV4, TRPA1 and ASICs.
•: ASIC is involved in the pronociceptive effect of pH-unadjusted, but not pH-adjusted MS solution.
•: TRPV1, TRPV4 and TRPA1 antagonists might be used for local treatment of injection-related pain.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.