Survivin does not influence the anti-apoptotic action of XIAP on caspase-9

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Survivin does not influence the anti-apoptotic action of XIAP on caspase-9

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作者：Franziska K. Zumbrä ; gel^a ; Dominik A. Machtens^a ; Ute Curth^a ; Carsten G.K. Lü ; der^b ; Thomas F. Reubold^a ; Susanne Eschenburg^a ; ^{Eschenburg.Susanne@mh-hannover.de}
关键词：Apoptosis ; Survivin ; XIAP ; Caspase inhibition ; Ubiquitination ; Smac
刊名：Biochemical and Biophysical Research Communications
出版年：2017
出版时间：22 January 2017
年：2017
卷：482
期：4
页码：530-535
全文大小：933 K
卷排序：482

文摘

Re-evaluation of survin's effect on the anti-caspase-9 activity of XIAP. Survivin does not enhance the inhibition of caspase-9 by XIAP in vitro. Survivin does not antagonize the inhibition of XIAP by Smac in vitro.