Investigation of gelling behavior of thiolated chitosan in alkaline condition and its application in stent coating

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Investigation of gelling behavior of thiolated chitosan in alkaline condition and its application in stent coating

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作者：Wei Zhao ; Ming Kong ; ^{kongming@ouc.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Chao Feng ; Xiaojie Cheng ; Ya Liu ; Xiguang Chen ; ^{xgchen@ouc.edu.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：Thiolated chitosan ; Gelation ; Alkaline condition ; Cardiovascular stent coating
刊名：Carbohydrate Polymers
出版年：2016
出版时间：20 January 2016
年：2016
卷：136
期：Complete
页码：307-315
全文大小：2132 K

文摘

•: Gelling behaviors of thiolated chitosan in alkaline condition were investigated.
•: Higher degree of thiolation, thiomer concentration or pH values promoted gelation.
•: Coagulation of chitosan and re-arrangement of disulfide bonds triggered gelation.
•: Thiolated chitosan (TCS) coated stent displayed parallel ridges and grooves.
•: TCS coated stent favored HUVECs adhesion and proliferation.

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