Apelin attenuates postburn sepsis via a phosphatidylinositol 3-kinase/protein kinase B dependent mechanism: A randomized animal study

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Apelin attenuates postburn sepsis via a phosphatidylinositol 3-kinase/protein kinase B dependent mechanism: A randomized animal study

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作者：Keqin Luo ; ^{keqinluodoc@126.com" class="auth_mail" title="E-mail the corresponding author} ; Huibao Long ^{longhuibao3hhsa@163.com" class="auth_mail" title="E-mail the corresponding author} ; Bincan Xu ^{xubincan42yae@yeah.net" class="auth_mail" title="E-mail the corresponding author} ; Yanling Luo ^{luoyanling45bs@163.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Burn ; Sepsis ; Apelin ; Inflammation ; PI3K/Akt
刊名：International Journal of Surgery
出版年：2015
出版时间：September 2015
年：2015
卷：21
期：Complete
页码：22-27
全文大小：801 K

文摘

•: Burn and burn sepsis induce significantly decreased apelin/APJ expression.
•: Apelin reduces inflammatory response and promotes survival after burn sepsis.
•: The effect of apelin on burn sepsis is PI3K/Akt dependent.

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