The abnormal status of uncarboxylated matrix Gla protein species represents an additional mortality risk in heart failure patients with vascular disease

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The abnormal status of uncarboxylated matrix Gla protein species represents an additional mortality risk in heart failure patients with vascular disease

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作者：Otto Mayer Jr^a ; ^b ; ^{mayero@fnplzen.cz" class="auth_mail" title="E-mail the corresponding author} ; Jitka Seidlerová ; ^a ; ^b ; Jiří ; Vaněk^a ; Petra Karnosová ; ^a ; ^b ; Jan Bruthans^a ; ^c ; Jan Filipovsk&yacute ; ^a ; ^b ; Peter Wohlfahrt^c ; ^d ; Renata Cí ; fková ; ^c ; ^d ; Jindra Windrichová ; ^e ; Marjo H.J. Knapen^f ; Nadja E.A. Drummen^f ; Cees Vermeer^f
关键词：Matrix γ-carboxyl glutamate protein (MGP) ; Heart failure ; dp-ucMGP ; t-ucMGP ; Mortality ; Atherovascular disease
刊名：International Journal of Cardiology
出版年：2016
出版时间：15 January 2016
年：2016
卷：203
期：Complete
页码：916-922
全文大小：441 K

文摘

•: Matrix Gla protein (MGP) is a natural calcification inhibitor.
•: Abnormal uncarboxylated MGP species were associated with mortality risk.
•: Highest risk represents co-incident abnormal MGP and brain natriuretic peptide.