VEGF-induced cell proliferation was suppressed by inhibiting the activity of ERK1/2.
•
RXM inhibits activation of VEGFR2 and ERK and downregulation of caveolin-1.
•
RXM inhibited TGF-β-induced VEGF secretion by ASM cells and BEAS-2B cells.
•
Our findings expand our knowledge of the role of RXM in airway remodelling.
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.