Effects of Epigallocatechin Gallate, an Antibacterial Cross-linking Agent, on Proliferation and Differentiation of Human Dental Pulp Cells Cultured in Collagen Scaffolds

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• 作者：Young-Sun Kwon ; MS^&lowast ; ; Hee-Jin Kim ; DDS ; MSD^&lowast ; ; Yun-Chan Hwang ; DDS ; PhD^&dagger ; ; Vinicius Rosa ; DDS ; PhD^&Dagger ; ; Mi-Kyung Yu ; DDS ; PhD^&lowast ; ; ^§ ; ; Kyung-San Min ; DDS ; PhD^&lowast ; ; ^§ ; ; ^{endomin@gmail.com}
• 关键词：Antibacterial ; collagen ; cross-linking ; epigallocatechin gallate ; odontogenic differentiation ; proliferation
• 刊名：Journal of Endodontics
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：43
• 期：2
• 页码：289-296
• 全文大小：1291 K
• 卷排序：43

文摘

Collagen scaffolds should be cross-linked to enhance their physical properties. Epigallocatechin gallate (EGCG) is used as a cross-linking agent and has an antibacterial effect. EGCG enhances the mechanical properties of collagen scaffold. EGCG promotes the proliferation and differentiation of hDPCs in collagen scaffolds. Cross-linking of collagen with EGCG is advantageous for regenerative endodontics.