The 91-205 amino acid region of AcMNPV ORF34 (Ac34), which comprises a potential C3H zinc finger, is required for its nuclear localization and optimal virus multiplication

详细信息    查看全文

• 作者：Jianxiang Qiu ; Zhimin Tang ; Meijin Yuan ; Wenbi Wu ; ^{wuwenbi3@mail.sysu.edu.cn} ; Kai Yang
• 关键词：Baculovirus ; AcMNPV ; ac34 ; Nuclear localization
• 刊名：Virus Research
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：228
• 期：Complete
• 页码：79-89
• 全文大小：2608 K
• 卷排序：228

文摘

The Autographa californica multiple nucleopolyhedrovirus Ac34 locates to the nucleus of Sf9 cells without the assistance of other viral proteins. The 91-205 amino acid region of Ac34 is required for its nuclear import. A potential C3H zinc finger located in amino acid 116-131 of Ac34 is essential for nuclear import. Nuclear localization of Ac34 is required for optimal virus replication.