Late onset MS is rare and few is known about neuro-retinal degeneration.
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OCT is a non-invasive method for measuring neuro-retinal degeneration in vivo.
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LOMS eyes display lower retinal layer thickness than healthy controls.
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Previous optic neuritis is a main contributor to retinal layer degeneration.
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In LOMS, levels of neuro-retinal degeneration are similar to age- or disease duration-matched NOMS.
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