Differences in Aβ brain networks in Alzheimer's disease and healthy controls

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• 作者：Huoqiang Duan^a ; Jiehui Jiang^a ; ^{jiangjiehui@shu.edu.cn} ; Jun Xu^a ; Hucheng Zhou^a ; Zhemin Huang^b ; ^{skywalkerhang@hotmail.com} ; Zhihua Yu^c ; ^{yzh1109@hotmail.com} ; Zhuangzhi Yan^a ; The Alzheimer's Disease Neuroimaging Initiative
• 关键词：Alzheimer's disease ; β-amyloid (Aβ)-cascade ; 11C-PiB PET ; Brain networks ; Graph theoretical
• 刊名：Brain Research
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：1655
• 期：Complete
• 页码：77-89
• 全文大小：1602 K
• 卷排序：1655

文摘

Sex, age and weight had no significant effect on the Aβ network. Explored the Aβ brain network in AD patients and Health Controls. Identified three altered hub regions: SFGdor. L, CUN.L and CAU.R. The three altered hubs could be biomarkers for AD classification.