Hopx distinguishes hippocampal from lateral ventricle neural stem cells

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Hopx distinguishes hippocampal from lateral ventricle neural stem cells

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作者：Deqiang Li^a ; Norifumi Takeda^a ; ¹ ; Rajan Jain^a ; Lauren J. Manderfield^a ; Feiyan Liu^a ; Li Li^a ; Stewart A. Anderson^b ; ^{sande@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; Jonathan A. Epstein^a ; ^{epsteinj@upenn.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：Hopx ; Homeodomain only protein X ; NSC ; Neural stem cells ; RGL cell ; Radial glia-like cell ; CC ; Corpus callosum ; CN ; Caudate nucleus ; DG ; Dentate gyrus ; LV ; Lateral ventricle ; OB ; Olfactory bulb ; LV-PZ ; LV proliferative zone ; SGZ ; Subgranular zone ; GFAP ; Glial fibrillary acidic protein ; BLBP ; Brain lipid-binding protein ; BrdU ; 5-Bromo-2&prime ; -deoxyuridine ; TAM ; Tamoxifen ; IHC ; Immunohistochemistry ; Tbr2 ; T-box brain protein 2 ; ASCL1 or Mash1 ; Achaete-scute homolog 1 ; DCX ; Doublecortin ; GFP ; Gree
刊名：Stem Cell Research
出版年：2015
出版时间：November 2015
年：2015
卷：15
期：3
页码：522-529
全文大小：2936 K

文摘

•: Hopx is expressed by neural stem cells (NSCs) in the adult hippocampus but not by NSCs in the lateral ventricle.
•: 10">Hopx + NSCs give rise to granule neurons in the dentate gyrus but not in the olfactory bulb.
•: 15">Hopx may regulate NSC maintenance and neurogenesis.

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