A neonatal mouse model for the evaluation of antibodies and vaccines against coxsackievirus A6

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A neonatal mouse model for the evaluation of antibodies and vaccines against coxsackievirus A6

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作者：Lisheng Yang^a ; ¹ ; Qunying Mao^b ; ¹ ; Shuxuan Li^a ; Fan Gao^b ; Huan Zhao^a ; Yajing Liu^a ; Junkai Wan^a ; Xiangzhong Ye^c ; Ningshao Xia^a ; Tong Cheng^a ; ^{tcheng@xmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Zhenglun Liang^b ; ^{lzhenglun@126.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Coxsackievirus A6 ; Animal model ; Antibody ; Vaccine
刊名：Antiviral Research
出版年：2016
出版时间：October 2016
年：2016
卷：134
期：Complete
页码：50-57
全文大小：2774 K

文摘

•: A neonatal mouse model of coxsackievirus A6 (CA6) infection was first established using a non-mouse-adapted CA6 strain.
•: CA6 showed strong tropism to skeletal muscles and skin.
•: The neonatal mouse model was successfully applied to evaluate a therapeutic mAb and a CA6 vaccine.

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