Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

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Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

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作者：Melanie Schirmer¹ ; ² ; Sanne P. Smeekens³ ; Hera Vlamakis¹ ; Martin Jaeger³ ; Marije Oosting³ ; Eric A. Franzosa¹ ; ² ; Rob ter Horst³ ; Trees Jansen³ ; Liesbeth Jacobs³ ; Marc Jan Bonder⁴ ; Alexander Kurilshikov⁴ ; ⁵ ; ⁶ ; Jingyuan Fu⁴ ; ⁷ ; Leo A.B. Joosten³ ; Alexandra Zhernakova⁴ ; Curtis Huttenhower¹ ; ² ; Cisca Wijmenga⁴ ; Mihai G. Netea³ ; ^{mihai.netea@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author} ; Ramnik J. Xavier¹ ; ⁸ ; ⁹ ; ¹⁰ ; ¹¹ ; ^{xavier@molbio.mgh.harvard.edu" class="auth_mail" title="E-mail the corresponding author}
刊名：Cell
出版年：2016
出版时间：3 November 2016
年：2016
卷：167
期：4
页码：1125-1136.e8
全文大小：1301 K

文摘

•: Database of predicted gut microbial associations with human cytokine responses
•: Microbiome-host interactions modulate inflammatory cytokine production capacity
•: Cytokine responses are associated with microbial taxonomic and functional features
•: Microbial metabolites modulate pathogen-induced TNFα and IFNγ responses

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