刊名:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
出版年:2017
出版时间:January 2017
年:2017
卷:1865
期:1
页码:55-64
全文大小:2473 K
卷排序:1865
文摘
We characterized SACOL1063 and CD1211 GNATs of unknown function. SACOL1063 preferentially acetylates the amino acid l-threonine. CD1211 prefers l-Thr, but can also acetylate l-Ser, O-acetyl-l-Ser, and l-Met. The SACOL1063 structure shows substantial conformational changes of an important loop. Two molecules of CoA were bound in donor and acceptor sites of SACOL1063.
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