A bicyclo-hairpin probe mediated strand displacement amplification strategy for label-free and sensitive detection of bleomycin

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A bicyclo-hairpin probe mediated strand displacement amplification strategy for label-free and sensitive detection of bleomycin

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作者：Huijuan Wang^aAuthor Vitae ; Wei Jiang^bAuthor Vitae ; Wei Li^aAuthor Vitae ; Lei Wang^a ; ^{wangl-sdu@sdu.edu.cn" class="auth_mail" title="E-mail the corresponding author}Author Vitae
关键词：Bicyclo-hairpin probe ; Strand displacement amplification ; Label-free ; Bleomycin
刊名：Sensors & Actuators: B. Chemical
出版年：2017
出版时间：January 2017
年：2017
卷：238
期：Complete
页码：318-324
全文大小：1389 K

文摘

•: A bicyclo-hairpin probe was designed ingeniously for bleomycin (BLM) recognition.
•: Based on BLM-induced DNA scission, a label-free fluorescent sensor for BLM detection was proposed.
•: The bicyclo-hairpin probe could silence trigger sequence to reduce non-specific hybridization.
•: The strategy showed a great potential application ability in clinical sample analysis.

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