Assessment of COPD severity by computed tomography: correlation with lung functional testing

详细信息    查看全文

• 作者：S ; ra Pauls ; Daniel Gulkin ; Sebastian Feuerlein ; Rainer Muche ; Stefan Kr&#xfc ; ger ; Stefan Andreas Schmidt ; Ekta Dharaiya ; Hans-J&#xfc ; rgen Brambs ; Martin Hetzel
• 关键词：Lung ; Computed tomography ; Emphysema ; Obstructive lung disease
• 刊名：Clinical Imaging
• 出版年：2010
• 出版时间：May-June 2010
• 年：2010
• 卷：34
• 期：3
• 页码：172-178
• 全文大小：309 K

文摘

CT scans of 474 patients with suspected chronic obstructive pulmonary disease (COPD) were retrospectively evaluated by automated software. There was a correlation between the total lung capacity (TLC) and the total lung volume (TLV) (r=.675, P<.001), between the TLC and the total emphysema volume (r=.571, P<.001), as well as between the TLC and the emphysema index (r=.532, P<.001), respectively. The correlation between the TLC and the TLV was dependent on the COPD severity according to the Global Initiative for Chronic Obstructive Lung Disease classification (χ²=6.3079, P=.043). The TLC allows a prediction of clinical illness severity.