Tandem transformations of tetrahydrobenzothieno[2,3-c]pyridines in the presence of activated alkynes

详细信息    查看全文

• 作者：Leonid G. Voskressensky ; Svetlana A. Kovaleva ; Tatiana N. Borisova ; Anna V. Listratova ; Alex ; r B. Eresko ; Valery S. Tolkunov ; Sergey V. Tolkunov ; Alexey V. Varlamov
• 关键词：Domino reactions ; Spiroannulation ; Ring expansion ; Thienopyridine ; Recyclization
• 刊名：Tetrahedron
• 出版年：2010
• 出版时间：27 November 2010
• 年：2010
• 卷：66
• 期：48
• 页码：9421-9430
• 全文大小：611 K

文摘

The reactivity of some new tetrahydrothienopyridines towards activated alkynes was investigated. A novel cascade cleavage-spiroannulation process, leading to the formation of previously unreported derivatives of 1′H-spiro[1-benzothiophene-3,4′-pyridine] was discovered and studied.