Fabrication of stable galactosylated alginate microcapsules via covalent coupling onto hydroxyl groups for hepatocytes applications

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Fabrication of stable galactosylated alginate microcapsules via covalent coupling onto hydroxyl groups for hepatocytes applications

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作者：Ruyun Lou^a ; ^b ; Weiting Yu^a ; ^{yuwt@dicp.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Yizhe Song^a ; ^b ; Ying Ren^a ; ^b ; Huizhen Zheng^a ; ^b ; Xin Guo^a ; Yunfei Lin^d ; Guoyu Pan^d ; Xiuli Wang^c ; ^{panpan1210@dicp.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Xiaojun Ma^a
关键词：Galactosylated alginate ; Hydroxyl groups ; Microcapsules ; Primary hepatocytes ; Biological artificial liver support systems
刊名：Carbohydrate Polymers
出版年：2017
出版时间：2 January 2017
年：2017
卷：155
期：Complete
页码：456-465
全文大小：2959 K

文摘

⿢: L-NH₂-OH-alginate based microcapsules were designed for hepatocyte applications.
⿢: L-NH₂-OH-alginate was fabricated via grafting LA onto hydroxyl groups of alginate.
⿢: The prepared microcapsules demonstrated an excellent stability.
⿢: The functional of primary hepatocytes in the prepared microcapsules was improved.

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