A simplified assay for the quantification of circulating activated protein C

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A simplified assay for the quantification of circulating activated protein C

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作者：Laura Martos^a ; ¹ ; ^{l.martos.marin@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Santiago Bonanad^a ; ^b ; ¹ ; ^{sbonanad@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Luis A. Ramó ; n^a ; ^{ramon_luinun@gva.es" class="auth_mail" title="E-mail the corresponding author} ; Ana-Rosa Cid^a ; ^b ; ^{cid_ana@gva.es" class="auth_mail" title="E-mail the corresponding author} ; Elena Bonet^a ; ^{bonetestruch@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Javier Corral^c ; ^{javier.corral@carm.es" class="auth_mail" title="E-mail the corresponding author} ; Manuel Miralles^d ; ^{miralles_manher@gva.es" class="auth_mail" title="E-mail the corresponding author} ; Francisco Españ ; a^a ; ^{espanya_fra@gva.es" class="auth_mail" title="E-mail the corresponding author} ; Silvia Navarro^a ; ^{navarro_silros@gva.es" class="auth_mail" title="E-mail the corresponding author} ; Pilar Medina^a ; ^{medina_pil@gva.es" class="auth_mail" title="E-mail the corresponding author}
关键词：APC ; activated protein C ; PC ; Protein C ; PCI ; protein C inhibitor ; VTE ; venous thromboembolism
刊名：Clinica Chimica Acta
出版年：2016
出版时间：1 August 2016
年：2016
卷：459
期：Complete
页码：101-104
全文大小：396 K

文摘

•: A simple and rapid assay for circulating activated protein C (APC) is proposed.
•: The recovery of APC added to plasma is more than 95%.
•: The assay correlates well (r = 0.954) with a previously reported assay.
•: The assay reduces the pre-analytical procedure and facilitates multicentre studies.

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