Plasmodium vivax vaccine research - we’ve only just begun

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• 作者：Wai-Hong Tham^a ; ^b ; James G. Beeson^c ; ^d ; Julian C. Rayner^e ; ^{jr9@sanger.ac.uk}
• 关键词：Malaria ; Plasmodium vivax ; Vaccine ; Erythrocyte invasion
• 刊名：International Journal for Parasitology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：47
• 期：2-3
• 页码：111-118
• 全文大小：688 K
• 卷排序：47

文摘

Blood-stage vaccine development is particularly critical for Plasmodium vivax. Large-scale protein arrays are powering an expansion in vaccine antigen screening. Structural studies allow antigen design to focus on critical pan-reactive epitopes. Further information on immune mechanisms and antigen diversity is needed.