The use of conformationally thermostabilised GPCRs in drug discovery: application to fragment, structure and biophysical techniques

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

The use of conformationally thermostabilised GPCRs in drug discovery: application to fragment, structure and biophysical techniques

详细信息查看全文

作者：Benjamin G Tehan ^{ben.tehan@heptares.com" class="auth_mail" title="E-mail the corresponding author} ; John A Christopher
刊名：Current Opinion in Pharmacology
出版年：2016
出版时间：October 2016
年：2016
卷：30
期：Complete
页码：8-13
全文大小：1212 K

文摘

•: Stabilised GPCRs (StaR proteins) enabling SBDD of GPCRs.
•: StaR proteins able to withstand harsh conditions seen in fragment-based drug discovery.
•: StaR proteins enabling kinetic and thermodynamic understanding of ligand/protein complexes.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.