Laccase- and electrochemically mediated conversion of triclosan: Metabolite formation and influence on antibacterial activity

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• 作者：Elham Jahangiri^a ; Bettina Seiwert^b ; Thorsten Reemtsma^b ; Dietmar Schlosser^a ; ^{dietmar.schlosser@ufz.de}
• 关键词：Electrochemical oxidation ; Ether cleavage ; Laccase ; Redox mediator ; Triclosan ; Syringaldehyde
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：549-558
• 全文大小：1168 K
• 卷排序：168

文摘

Laccase oxidation of triclosan (TCS) led to oligomerization and ether cleavage. Ether cleavage was more prominent during electrochemical TCS oxidation. Syringaldehyde (SYD) promoted TCS ether cleavage by laccase. SYD was consumed thus not acting as a recyclable “true” laccase redox mediator. Dimethoxybenzoquinone formed from SYD contributes to SYD-laccase systems' toxicity.