Expression of nuclear Methyl-CpG binding protein 2 (Mecp2) is dependent on neuronal stimulation and application of Insulin-like growth factor 1

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Expression of nuclear Methyl-CpG binding protein 2 (Mecp2) is dependent on neuronal stimulation and application of Insulin-like growth factor 1

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作者：Daniela Tropea^a ; ^{tropead@tcd.ie" class="auth_mail" title="E-mail the corresponding author} ; ^{tropea@mit.edu" class="auth_mail" title="E-mail the corresponding author} ; Niall Mortimer^b ; Stefania Bellini^a ; Ines Molinos^a ; Albert Sanfeliu^a ; Stephen Shovlin^a ; Donna McAllister^a ; Michael Gill^a ; Kevin Mitchell^b ; Aiden Corvin^a
关键词：Mecp2 ; MethylCpG-binding protein 2 ; IGF1 ; insulin-like growth factor 1
刊名：Neuroscience Letters
出版年：2016
出版时间：16 May 2016
年：2016
卷：621
期：Complete
页码：111-116
全文大小：716 K

文摘

•: Mecp2 protein nuclear expression is dependent on neuronal stimulation.
•: Increase in the cellular activity induce a decrease in Mecp2 nuclear staining.
•: Insulin-like factor 1 (IGF1) administration induces an increase in Mecp2 expression.

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