Induction of micronuclei and alteration of gene expression by an organomodified clay in HepG2 cells

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Induction of micronuclei and alteration of gene expression by an organomodified clay in HepG2 cells

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作者：Sara Maisanaba^a ; ^{saramh@us.es" class="auth_mail" title="E-mail the corresponding author} ; Klara Hercog^b ; Natalia Ortuñ ; o^c ; Á ; ngeles Jos^a ; Bojana Žegura^b
关键词：Modified clay ; Cytokinesis block micronucleus assay ; Real-time quantitative PCR ; HepG2
刊名：Chemosphere
出版年：2016
出版时间：July 2016
年：2016
卷：154
期：Complete
页码：240-248
全文大小：976 K

文摘

•: Clay2 is a new organomodified clay intented to food industry.
•: Clay2 induces micronucleus and nuclear buds, but not nuclear bridges in HepG2 cells.
•: Clay2 induces changes in the gene expression.
•: Gene alteration is presented mainly after 24 h of exposure to Clay2.

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