Depletion of juvenile hormone esterase extends larval growth in Bombyx mori

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• 作者：Zhongjie Zhang^a ; ^b ; Xiaojing Liu^b ; Takahiro Shiotsuki^c ; Zhisheng Wang^d ; Xia Xu^a ; Yongping Huang^b ; Muwang Li^e ; Kai Li^a ; ^{kaili@bio.ecnu.edu.cn} ; Anjiang Tan^b ; ^{ajtan01@sibs.ac.cn}
• 关键词：Bombyx mori ; Juvenile hormone esterase ; CRISPR/Cas9
• 刊名：Insect Biochemistry and Molecular Biology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：81
• 期：Complete
• 页码：72-79
• 全文大小：2373 K
• 卷排序：81

文摘

JHE depletion extended larval periods and created giant larvae and cocoons in Bombyx mori. Activated TOR pathway was responsible for extension of larval periods in JHE mutants. The transgenic CRISPR/Cas9 system provided a promising approach for analysing the actions of JH.