Identification of immunogenic proteins from ovarian tissue and recognized in larval extracts of Rhipicephalus (Boophilus) microplus, through an immunoproteomic approach

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Identification of immunogenic proteins from ovarian tissue and recognized in larval extracts of Rhipicephalus (Boophilus) microplus, through an immunoproteomic approach

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作者：Patricia Berenice Ramí ; rez Rodrí ; guez^a ; ^{acineto123@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Rodrigo Rosario Cruz^b ; ^{rockdrig@yahoo.com.mx" class="auth_mail" title="E-mail the corresponding author} ; Delia Iné ; s Domí ; nguez Garcí ; a^b ; ^{deliadomgar@yahoo.com.mx" class="auth_mail" title="E-mail the corresponding author} ; Rodolfo Herná ; ndez Gutié ; rrez^a ; ^{rhgutierrez@ciatej.mx" class="auth_mail" title="E-mail the corresponding author} ; Rodolfo Esteban Lagunes Quintanilla^c ; ^{rodolfo.lagunes@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Daniel Ortuñ ; o Sahagú ; n^d ; ^{daniel.ortuno.sahagun@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Celia Gonzá ; lez Castillo^d ; ^{celia_glz@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Abel Gutié ; rrez Ortega^a ; ^{aortega@ciatej.mx" class="auth_mail" title="E-mail the corresponding author} ; Sara Elisa Herrera Rodrí ; guez^a ; ^{sherrera@ciatej.mx" class="auth_mail" title="E-mail the corresponding author} ; Adriana Vallejo Cardona^a ; ^{avallejo@ciatej.mx" class="auth_mail" title="E-mail the corresponding author} ; Moisé ; s Martí ; nez Velá ; zquez^a ; ^{moisesmartinezv@yahoo.com.mx" class="auth_mail" title="E-mail the corresponding author}
关键词：Tick ; Boophilus microplus ; Ovary ; Immunogen ; Vitellogenin ; Vaccine
刊名：Experimental Parasitology
出版年：2016
出版时间：November 2016
年：2016
卷：170
期：Complete
页码：227-235
全文大小：1131 K

文摘

•: A classical approach immunizing cattle with total ovarian proteins was followed.
•: The detection of ovarian proteins was achieved by ELISA plates coated with proteins from larval homogenates.
•: Several immunogenic proteins such as Vitellogenins and yolk Cathepsin were identified.
•: Vitellogenin-1 and Vitellogenin-2 transcripts are synthesized in the ovaries of R. microplus.
•: Vitellogenins represent attractive candidates for development of anti-tick vaccines.