Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor

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• 作者：Tristan Stevens¹ ; Sisi Song¹ ; John B. Bruning ; Amanda Choo ; Simon W. Baxter ; ^{simon.baxter@adelaide.edu.au}
• 关键词：Bt toxin ; Cry1Ac ; Plutella xylostella ; Insecticide resistance ; Insecticide receptor
• 刊名：Insect Biochemistry and Molecular Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：80
• 期：Complete
• 页码：61-70
• 全文大小：1297 K
• 卷排序：80

文摘

We assessed whether the P. xylostella ABCC2 protein is a functional Bt receptor. Px-ABCC2 was transformed into Drosophila and expressed in the midgut. Expressing Px-ABCC2 rendered Drosophila susceptible to Cry1Ac toxin and protoxin. M. sexta cadherin peptides synergised Cry1Ac more effectively than P. xylostella peptides.