Intermittent Haemoptysis due to an Aortobronchial Fistula in a Warmblood Mare

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• 作者：H. Versnaeyen^&lowast ; ; ^{Han.Versnaeyen@ugent.be" class="auth_mail" title="E-mail the corresponding author} ; V. Saey^&lowast ; ; D. Vermeiren^&dagger ; ; K. Chiers^&lowast ; ; R. Ducatelle^&lowast ;
• 关键词：aortic aneurysm ; aortobronchial fistula ; horse ; pseudoaneurysm
• 刊名：Journal of Comparative Pathology
• 出版年：2016
• 出版时间：August-October 2016
• 年：2016
• 卷：155
• 期：2-3
• 页码：213-217
• 全文大小：1408 K

文摘

A 7-year-old warmblood mare showed sudden onset of mild intermittent haemoptysis. Clinical examination revealed no significant abnormalities. Haematological examination showed mild anaemia, hypoalbuminaemia and neutrophilia. Coagulation tests were normal. Endoscopic examination revealed unilateral pulmonary haemorrhage with blood clots in the bronchi and trachea. Treatment with antibiotics was started and the horse was given stable rest. Two weeks later, the horse was found dead with blood and frothy sputum leaking from the nostrils. Post-mortem examination revealed a large thoracic aortic aneurysm communicating with a pseudoaneurysm that had formed a fistula into a right bronchial branch. Microscopical examination of the aneurysm showed extensive medial fibrosis with prominent degeneration, fragmentation and mineralization of the elastic fibres and deposition of mucoid material in the tunica media. The pseudoaneurysm was lined by collagen bundles admixed with fibroblasts and a small amount of adipose tissue. Aortobronchial fistula is a rare condition in man that is usually associated with primary aortic pathology, most often aneurysms. To the authors' knowledge this is the first case of a fatal aortobronchial fistula in a horse or any other animal species.