Dynamics of epileptic activity in a peculiar case of childhood absence epilepsy and correlation with thalamic levels of GABA

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Dynamics of epileptic activity in a peculiar case of childhood absence epilepsy and correlation with thalamic levels of GABA

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作者：Alberto Leal^a ; ^{a.leal@neuro.pt" class="auth_mail" title="E-mail the corresponding author} ; José ; P. Vieira^b ; Ricardo Lopes^c ; Rita G. Nunes^d ; Só ; nia I. Gonç ; alves^e ; Fernando Lopes da Silva^f ; ^g ; Patrí ; cia Figueiredo^g
关键词：Childhood absence epilepsy ; GABA ; Thalamus ; Human
刊名：Epilepsy & Behavior Case Reports
出版年：2016
出版时间：2016
年：2016
卷：5
期：Complete
页码：57-65
全文大小：4627 K

文摘

•: A childhood absence epilepsy case with single hemispheric involvement is described.
•: Thalamic GABA/Cr ratio of affected versus reference hemisphere was increased to 2.57.
•: A similar ratio between occipital cortex ROIs was 1.09, which was within normal range.
•: We propose a role for increased thalamic GABA in childhood absence epilepsy.

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