The Molecular Taxonomy of Primary Prostate Cancer
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Comprehensive molecular analysis of 333 primary prostate carcinomas

Seven subtypes defined by ETS fusions or mutations in m>SPOPm>, m>FOXA1m>, and m>IDH1m>

Substantial epigenetic heterogeneity, including a hypermethylated m>IDH1m> mutant subset

Presumed actionable lesions in the PI3K, MAPK, and DNA repair pathways

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