PPARγ is regulated by miR-27b-3p negatively and plays an important role in porcine oocyte maturation

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PPARγ is regulated by miR-27b-3p negatively and plays an important role in porcine oocyte maturation

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作者：Chunlei Song^a ; ¹ ; Jing Yao^b ; ^c ; ¹ ; Chunwei Cao^b ; ^c ; Xiaojuan Liang^a ; Jiaojiao Huang^b ; ^c ; Ziqiang Han^b ; ^d ; Yang Zhang^b ; ^c ; Guosong Qin^b ; ^c ; Cong Tao^a ; Chengbo Li^e ; Haoran Yang^f ; Jianguo Zhao^b ; ^c ; Kui Li^a ; Yanfang Wang^a ; ^{wangyanfang@caas.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：Pig ; miRNA ; Oocyte maturation ; PPARγ ; Fatty acid metabolism
刊名：Biochemical and Biophysical Research Communications
出版年：2016
出版时间：14 October 2016
年：2016
卷：479
期：2
页码：224-230
全文大小：1938 K

文摘

•: Profiling of miRNAs in porcine GV and MII oocytes.
•: Fatty acid metabolism pathway is over-represented during porcine oogenesis.
•: PPARγ is regulated by miR-27b-3p negatively.
•: PPARγ promotes the rate of porcine oocyte maturation and blastocyst in vitro.

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