Cell Migration: Making the Waves

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• 作者：Jan Mü ; ller ; Michael Sixt ; ^{sixt@ist.ac.at}
• 刊名：Current Biology
• 出版年：2017
• 出版时间：9 January 2017
• 年：2017
• 卷：27
• 期：1
• 页码：R24-R25
• 全文大小：242 K
• 卷排序：27

文摘

Coordinated changes of cell shape are often the result of the excitable, wave-like dynamics of the actin cytoskeleton. New work shows that, in migrating cells, protrusion waves arise from mechanochemical crosstalk between adhesion sites, membrane tension and the actin protrusive machinery.