Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae

详细信息    查看全文

• 作者：Makoto Kitamura ; Peter J. Schupp ; Yoshikatsu Nakano ; Daisuke Uemura
• 关键词：Luminaolide ; Enhancer ; Hydrolithon reinboldii ; Leptastrea purpurea ; Coral larvae ; Crustose coralline algae (CCA)
• 刊名：Tetrahedron Letters
• 出版年：2009
• 出版时间：25 November 2009
• 年：2009
• 卷：50
• 期：47
• 页码：6606-6609
• 全文大小：212 K

文摘

A new metamorphosis-enhancing macrodiolide, luminaolide (1), was isolated from the crustose coralline algae (CCA) Hydrolithon reinboldii. Its structure was determined by spectroscopic analysis. A fraction (1.30 μg/mL) eluted with 80 % aqueous MeOH by ODS gel column chromatography of the same CCA extract induced larval metamorphosis (25.9 ± 7.4 % ) against Leptastrea purpurea, and its metamorphosis-inducing activity was further enhanced to 92.6 ± 2.9 % with the addition of 1 (25.6 ng/mL).