The role of neuropeptide CART in the lateral hypothalamic-ventral tegmental area (LH-VTA) circuit in motivation

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The role of neuropeptide CART in the lateral hypothalamic-ventral tegmental area (LH-VTA) circuit in motivation

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作者：Amita R. Somalwar^a ; ¹ ; Gajanan P. Shelkar^a ; ¹ ; Nishikant K. Subhedar^b ; ^{nksubhedar@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Dadasaheb M. Kokare^a ; ^{kokaredada@yahoo.com" class="auth_mail" title="E-mail the corresponding author}
关键词：CART ; Reward ; LH-MFB ; pVTA ; AcbSh
刊名：Behavioural Brain Research
出版年：2017
出版时间：15 January 2017
年：2017
卷：317
期：Complete
页码：340-349
全文大小：4088 K

文摘

class="label">•: Intracranial self-stimulation (ICSS) was facilitated by CART.
class="label">•: ICSS resulted in robust activation of CART cells in the LH.
class="label">•: ICSS induced synaptic plasticity in CART system in reward circuit.
class="label">•: Rats can be conditioned to self-administer CART in pVTA.
class="label">•: CART neurons of LH-MFB may process motivation via the mesolimbic dopamine pathway.

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