Does maternal MDR1 C1236T polymorphism have an effect on placental arsenic levels?

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Does maternal MDR1 C1236T polymorphism have an effect on placental arsenic levels?

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作者：Dilek Kaya-Akyü ; zlü ; ; ^{kayadilek79@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{kaya@ankara.edu.tr" class="auth_mail" title="E-mail the corresponding author} ; Zeliha Kayaaltı ; Derya Doğan ; Tü ; lin Sö ; ylemezoğlu
关键词：Arsenic ; Phospho-glycoprotein (P-gp) ; Human multidrug resistance 1 (MDR1) ; MDR1 C1236T polymorphism ; Placental tissue
刊名：Environmental Toxicology and Pharmacology
出版年：2016
出版时间：January 2016
年：2016
卷：41
期：Complete
页码：142-146
全文大小：534 K

文摘

class="label">class="boldFont">•: This was the first study evaluating the effect of MDR1 C1236T polymorphism on placental arsenic levels.
class="label">class="boldFont">•: Placental arsenic levels of MDR1 C1236T variant mothers were found higher than those of wild type.
class="label">class="boldFont">•: Fetuses of mothers with TT genotype may be more susceptible to arsenic toxicity.

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