Reveal the molecular signatures of hepatocellular carcinoma with different sizes by iTRAQ based quantitative proteomics

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Reveal the molecular signatures of hepatocellular carcinoma with different sizes by iTRAQ based quantitative proteomics

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作者：Yingchao Wang^a ; ^b ; Hongzhi Liu^a ; ^b ; ^c ; Dong Liang^a ; ^b ; ^c ; Yao Huang^a ; ^b ; ^c ; Yongyi Zeng^a ; ^b ; ^c ; Xiaohua Xing^a ; ^b ; Jiangbao Xia^a ; ^b ; Minjie Lin^a ; ^b ; Xiao Han^d ; Naishun Liao^a ; ^b ; Xiaolong Liu^a ; ^b ; ^{xiaoloong.liu@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jingfeng Liu^a ; ^b ; ^c ; ^{drjingfeng@126.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Hepatocellular carcinoma ; Quantitative proteomics ; Tumor size ; Tumor growth ; iTRAQ
刊名：Journal of Proteomics
出版年：2017
出版时间：6 January 2017
年：2017
卷：150
期：Complete
页码：230-241
全文大小：1441 K

文摘

class="label">•: The iTRAQ approach was applied to study the hepatocellular carcinoma (HCC) with different sizes.
class="label">•: Protein alternations were proved in the HCC comparing to noncancerous tissues.
class="label">•: Different molecular alternations and specific signalings were involved in different HCC subtypes.
class="label">•: A group of proteins correlated with the tumor size, which might be potential targets for study tumor growth of HCC.

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