Accurate annotation of protein-coding genes in mitochondrial genomes

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Accurate annotation of protein-coding genes in mitochondrial genomes

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作者：Marwa Al Arab^a ; ^b ; ^h ; ^{marwa@bioinf.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author} ; Christian Hö ; ner zu Siederdissen^a ; ^b ; ^c ; ^{choener@bioinf.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author} ; Kifah Tout^h ; ^{ktout@ul.edu.lb" class="auth_mail" title="E-mail the corresponding author} ; Abdullah H. Sahyoun^a ; ^b ; ^h ; ⁱ ; ^{abdullah.sahyoun@tron-mainz.de" class="auth_mail" title="E-mail the corresponding author} ; Peter F. Stadler^a ; ^b ; ^c ; ^d ; ^e ; ^f ; ^g ; ^{studla@bioinf.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author} ; Matthias Bernt^a ; ^j ; ^{bernt@informatik.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author}
关键词：Protein coding genes ; Metazoa ; Mitochondrial DNA ; Annotation ; Hidden Markov models
刊名：Molecular Phylogenetics and Evolution
出版年：2017
出版时间：January 2017
年：2017
卷：106
期：Complete
页码：209-216
全文大小：996 K

文摘

class="label">•: An automated pipeline for fast de-novo annotation of mitochondrial protein-coding genes is presented.
class="label">•: The method generates taxon-specific enhanced multiple sequence alignments (MSA) and corresponding HMMs.
class="label">•: Automatic frameshift correction method.
class="label">•: Detailed analysis of the frameshifts in nad3 of the Testudines-Archosauria.

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