Botulinum toxin as early intervention for spasticity after stroke or non-progressive brain lesion: A meta-analysis

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Botulinum toxin as early intervention for spasticity after stroke or non-progressive brain lesion: A meta-analysis

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作者：Raymond L. Rosales ; MD ; PhD^a ; ^b ; ^c ; ^{rlrosalesmd88@gmail.com" class="auth_mail" title="E-mail the corresponding author} (Professor) ; Fran Efendy^b ; ^{franefendy@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ericka SA Teleg^a ; ^{rickateleg@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Mary MD Delos Santos^c ; ^{marymildred8888@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Mary CE Rosales^d ; ^{kamille_35@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Marc Ostrea^c ; ^{marc_ostrea@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Michelle J Tanglao^c ; ^{mmjoya@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Arlene R. Ng^b ; ^c ; ^{arngmd@gmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：AE ; adverse event ; ARAT ; Action Research Arm Test ; BoNT-A ; botulinum toxin type A ; DS ; Disability scale ; GAS ; Goal Attainment Scaling ; MAS ; Modified Ashworth Scale ; PSS ; post-stroke spasticity ; ROM ; range of motion ; SMD ; standard mean difference ; VAS ; visual analogue scale
刊名：Journal of the Neurological Sciences
出版年：2016
出版时间：15 December 2016
年：2016
卷：371
期：Complete
页码：6-14
全文大小：1110 K

文摘

class="label">•: Spasticity is a frequently observed accompanying motor impairment in stroke.
class="label">•: There are few data on the early application of BoNT-A treatment for PSS.
class="label">•: Early intervention with BoNT-A reduced muscle tone in PSS in six randomised controlled trials
class="label">•: There was some evidence of pain reduction, but no improvements in disability and function.
class="label">•: Early BoNT-A treatment with neurorehabilitation therapy may improve PSS and reduce impairment.

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