T1-weighted MR imaging of glioma at 3T: a comparative study of 3D MPRAGE vs. conventional 2D spin-echo imaging

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• 作者：Toshiki Dodo^a ; ^{tdodo@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Tomohisa Okada^a ; ^{tomokada@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Akira Yamamoto^a ; ^{yakira@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Mitsunori Kanagaki^a ; ^{mitsuk@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yasutaka Fushimi^a ; ^{yfushimi@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Tsutomu Okada^a ; ^{tokadat@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Akihiko Sakata^a ; ^{asakata@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yoshiki Arakawa^b ; ^{yarakawa@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Susumu Miyamoto^b ; ^{miy@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Kaori Togashi^a ; ^{ktogashi@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}
• 关键词：MRI ; MPRAGE ; contrast enhancement ; glioma
• 刊名：Clinical Imaging
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：40
• 期：6
• 页码：1257-1261
• 全文大小：523 K

文摘

This study aims to investigate difference between magnetization-prepared rapid gradient-echo imaging (MPRAGE) and spin-echo (SE) imaging for evaluating glioma on pre-contrast-enhanced (CE) and post-CE T1-weighted images at 3 T.

Materials and methods

We retrospectively assessed pre-CE and post-CE T1-weighted images for tumor contrast in 64 consecutive glioma patients.

Results

In the nonenhancing tumors, the contrast was significantly clearer in MPRAGE than SE. In the enhancing tumors, post-CE contrast ratio was significantly higher in SE than MPRAGE, but when subtraction images are evaluated, the difference got smaller.

Conclusion

MPRAGE can be a good substitute of SE for T1-weighted imaging of glioma.