Safety of histamine-2 receptor blockers in hospitalized VLBW infants

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Safety of histamine-2 receptor blockers in hospitalized VLBW infants

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作者：Andrew Romaine^a ; ^{aromaine@live.unc.edu" class="auth_mail" title="E-mail the corresponding author} ; Daniel Ye^a ; ^{daniel.ye@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Zachary Ao^a ; ^{aosterrr@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Francia Fang^a ; ^{francia.fang@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Octavious Johnson^a ; ^{octaviousjohnson33@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Taylor Blake^a ; ^{tsblake015@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Daniel K. Benjamin Jr.^a ; ^{danny.benjamin@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author} ; C. Michael Cotten^a ; ^{michael.cotten@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Daniela Testoni^a ; ^{danielatestoni@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Reese H. Clark^b ; ^{Reese_H_Clark@us.MEDNAX.com" class="auth_mail" title="E-mail the corresponding author} ; Vivian H. Chu^a ; ^{vivian.chu@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; P. Brian Smith^a ; ^{brian.smith@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Christoph P. Hornik^a ; ^{christoph.hornik@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author} ; for the Best Pharmaceuticals for Children Act &ndash ; Pediatric Trials Network
关键词：Histamine-2 receptor antagonists ; H2 blockers ; Infants ; Necrotizing enterocolitis
刊名：Early Human Development
出版年：2016
出版时间：August 2016
年：2016
卷：99
期：Complete
页码：27-30
全文大小：246 K

文摘

class="label">•: Using a multicenter electronic health record based clinical database, we characterized histamine-2 receptor (H₂) blocker use in very low birth weight (VLBW) infants.
class="label">•: We found that despite decreasing use over time, VLBW infants frequently remained exposed to H2 blockers and that exposure was associated with increased morbidity and mortality.