Local brain activity persists during apparently generalized postictal EEG suppression
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Postictal generalized EEG suppression is usually determined with scalp EEG (s-PGES).

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Local brain activity in deeper brain structures may be missed.

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Intracranial EEG was examined in generalized convulsive seizures (GCS) with s-PGES.

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In most GCS, local brain activity persisted or reemerged before s-PGES resolved.

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Potential implications for the pathophysiology of SUDEP are discussed.

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