In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity

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In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity

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作者：Stephan Halle¹ ; ^{halle.stephan@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author} ; Kirsten Anja Keyser² ; Felix Rolf Stahl¹ ; ¹⁰ ; Andreas Busche² ; ¹¹ ; Anja Marquardt² ; ¹² ; Xiang Zheng¹ ; Melanie Galla³ ; Vigo Heissmeyer⁴ ; ⁵ ; Katrin Heller¹ ; Jasmin Boelter¹ ; Karen Wagner² ; Yvonne Bischoff¹ ; Rieke Martens¹ ; Asolina Braun¹ ; ¹³ ; Kathrin Werth¹ ; Alexey Uvarovskii⁶ ; Harald Kempf⁶ ; Michael Meyer-Hermann⁶ ; ⁷ ; Ramon Arens⁸ ; Melanie Kremer⁹ ; Gerd Sutter⁹ ; Martin Messerle² ; Reinhold Fö ; rster¹ ; ^{foerster.reinhold@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author}
刊名：Immunity
出版年：2016
出版时间：16 February 2016
年：2016
卷：44
期：2
页码：233-245
全文大小：3947 K

文摘

class="label">•: Two-photon imaging indicates that CTLs kill 2–16 virus-infected cells per day
class="label">•: CTLs form kinapses rather than stable synapses when killing virus-infected cells
class="label">•: Some CTL contacts trigger long-lasting calcium fluxes in virus-infected cells
class="label">•: CTLs can cooperate during killing of virus-infected cells

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