Evaluation of biodegradable polymer conduits - poly(l-lactic acid) - for guiding sciatic nerve regeneration in mice

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Evaluation of biodegradable polymer conduits - poly(l-lactic acid) - for guiding sciatic nerve regeneration in mice

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作者：Camila Oliveira Goulart^a ; ^b ; ¹ ; Fá ; tima Rosalina Pereira Lopes^b ; ¹ ; Zulmira Oliveira Monte^b ; ^f ; Severino Valentim Dantas Jr.^a ; Allana Souto^b ; Jú ; lia Teixeira Oliveira^b ; Fernanda Martins Almeida^b ; ^d ; Chiara Tonda-Turo^c ; Cristina Cardoso Pereira^e ; Cristiano Piacsek Borges^e ; Ana Maria Blanco Martinez^a ; ^b ; ^{martinez@histo.ufrj.br" class="auth_mail" title="E-mail the corresponding author}
关键词：Nerve conduits ; Poly(l-lactic acid) ; Ischiatic nerve ; Nerve regeneration ; Mice
刊名：Methods
出版年：2016
出版时间：15 April 2016
年：2016
卷：99
期：Complete
页码：28-36
全文大小：3701 K

文摘

•: The manufacture of a PLA polymer for nerve regeneration is proposed.
•: PLA membranes provide a good substrate for SC and MSC adhesion.
•: The efficacy of PLA polymer is compared with PCL polymer.
•: We report that PLA conduit improves nerve regeneration and motor function.

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