• 作者：Twinkle Ghia ; FRACP^a ; Manoj Kanhangad ; MBBS^a ; Angela Jane Alessandri ; FRACP^b ; Glynis Price ; FRACP^c ; Parshotam Gera ; FRACS^d ; Lakshmi Nagarajan ; FRACP^a ; ^e ; ^{lakshmi.Nagarajan@health.wa.gov.au" class="auth_mail" title="E-mail the corresponding author}
• 关键词：opsoclonus myoclonus ataxia ; type I diabetes mellitus ; neuroblastoma ; anti-GAD antibodies
• 刊名：Pediatric Neurology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：55
• 期：Complete
• 页码：68-70
• 全文大小：241 K

Patient description

This 17-month-old child presented with opsoclonus-myoclonus-ataxia syndrome. Investigations revealed a thoracic neuroblastoma. Eleven days later, she re-presented with diabetic ketoacidosis. The neuroblastoma was resected, and she was given immunotherapy. At 12 months' follow-up, her neurological signs and symptoms have significantly improved, but she continues to be insulin dependent.

Discussion

This child expands the clinical spectrum of autoimmune disorders associated with opsoclonus-myoclonus-ataxia syndrome.