Efficient synthesis of 5-substituted-3-pyridazine carbonitrile via regioselective Reissert-type reaction
文摘

A series of 5-substituted-3-pyridazine carbonitrile derivatives were synthesized.

One-pot two-step regioselective Reissert-type reaction was used.

Regioselective cyanation of 4-substituted pyridazine was studied for the first time.

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