nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation

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nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation

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作者：Sijie Chen ; Hefei Zhang ; Fenghua Wang ; Wei Zhang ; Gang Peng ; ^{gangpeng@fudan.edu.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：Sex determination ; nr0b1 ; DAX1 ; Somatic cell ; Zebrafish
刊名：Molecular and Cellular Endocrinology
出版年：2016
出版时间：15 September 2016
年：2016
卷：433
期：Complete
页码：105-116
全文大小：2345 K

文摘

•: nr0b1 mutation in zebrafish led to female-to-male sex reversal.
•: nr0b1 gene did not regulate sex determination via tp53-mediated apoptosis.
•: nr0b1 regulated somatic cell differentiation and cell proliferation in zebrafish.

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