Antimicrobial effect of salicylamide derivatives against intestinal sulfate-reducing bacteria
文摘

Sulfate-reducing bacteria are involved in the initiation and maintenance of inflammatory bowel disease.

Salicylamide derivatives had MIC values in the range 0.22–0.35 μM against Desulfovibrio piger Vib-7.

Salicylamide derivatives had MIC values in the range 0.27–8.52 μM against Desulfomicrobium sp. Rod-9.

Lipophilicity was recognized as a significant parameter affecting biological activities.

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